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Monoclonal Antibody to Progesterone Receptor (Marker of Progestin Dependence) (Clone : PR501)

Selected Variant

36-1559-100

Size: 100 µg

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) . Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.

Product Specifications

Product Name Alternative

PGR||NR3C3

Gene Name

PGR

Gene ID

5241

UniProt

P06401

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Progesterone Receptor protein

Target Antigen

Progesterone Receptor (Marker of Progestin Dependence)

Clonality

Monoclonal

Clone

PR501

Applications

WB, IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western Blot (1-2ug/ml for 2 hours at Room Temp) ; Immunohistochemistry (Formalin-fixed) (1-2ug/ml) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)

Isotype

Mouse IgG1, kappa

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