Monoclonal Antibody to Progesterone Receptor (Marker of Progestin Dependence) (Clone : PR484)
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) . Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Product Specifications
Product Name Alternative
PGR||NR3C3
Gene Name
PGR
Gene ID
5241
UniProt
P06401
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Progesterone Receptor protein
Target Antigen
Progesterone Receptor (Marker of Progestin Dependence)
Clonality
Monoclonal
Clone
PR484
Applications
IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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