Monoclonal Antibody to NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) (NGFR5 + NTR/912)
Selected Variant
36-1518-100
Size: 100 µg
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Product Specifications
Product Name Alternative
NGFR||TNFRSF16
Gene Name
NGFR
Gene ID
4804
UniProt
P08138
Host
Mouse
Reactivity
Human
Immunogen
NGFR from A875 melanoma cells (NGFR5) ; Recombinant human p75 NGFR protein (NTR/912)
Target Antigen
NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker)
Clonality
Monoclonal
Clone
NGFR5 + NTR/912
Applications
IHC, FACS, IF
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa + Mouse IgG1, kappa
Price
Frequently Asked Questions
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