Monoclonal Antibody to MUC5AC (Mucin 5AC / Gastric Mucin) (Clone : SPM297)
Selected Variant
36-1463-100
Size: 100 µg
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC) . Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Product Specifications
Product Name Alternative
MUC5AC||MUC5
Gene Name
MUC5AC
Gene ID
4586
UniProt
P98088
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
M1 mucin prepaRation from the fluid of an ovarian mucinous cyst belonging to an O Le (a-b) patient
Target Antigen
MUC5AC (Mucin 5AC / Gastric Mucin)
Clonality
Monoclonal
Clone
SPM297
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Price
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