Monoclonal Antibody to MUC2 (Mucin 2) (Clone : SPM513)
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2) . This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro) . Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Product Specifications
Product Name Alternative
MUC2||SMUC
Gene Name
MUC2
Gene ID
4583
UniProt
Q02817
Host
Mouse
Reactivity
Human
Immunogen
A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH.
Target Antigen
MUC2 (Mucin 2)
Clonality
Monoclonal
Clone
SPM513
Applications
IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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