Monoclonal Antibody to Ep-CAM / CD326 (Epithelial Marker) (PAN-EpCAM (Cocktail) )
Selected Variant
36-1411-100
Size: 100 µg
It is a cocktail of four highly specific monoclonal antibodies (EGP40/826, EGP40/837, EGP40/1110, EGP40/1120) that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (Ep-CAM) . It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or Ep-CAM. Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Product Specifications
Product Name Alternative
EPCAM||GA733-2||M1S2||M4S1||MIC18||TACSTD1||TROP1
Gene Name
EPCAM
Gene ID
4072
UniProt
P16422
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Ep-CAM protein (full-length and fragments)
Target Antigen
Ep-CAM / CD326 (Epithelial Marker)
Clonality
Monoclonal
Clone
PAN-EpCAM (Cocktail)
Applications
FACS, IF, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1 s, kappa
Price
Frequently Asked Questions
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