Monoclonal Antibody to Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) (KRT7/760 + OV-TL12
Selected Variant
36-1350-100
Size: 100 µg
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-) .
Product Specifications
Product Name Alternative
KRT7||SCL
Gene Name
KRT7
Gene ID
3855
UniProt
P08729
Host
Mouse
Reactivity
Human, Rat
Immunogen
Recombinant full-length human KRT7 protein (KRT7/760) ; OTN 11, ovarian carcinoma cell line (OV-TL12/30)
Target Antigen
Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker)
Clonality
Monoclonal
Clone
KRT7/760 + OV-TL12/30
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa + Mouse IgG1, kappa
Price
Frequently Asked Questions
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