Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (Clone : KIT/982)
Selected Variant
36-1336-100
Size: 100 µg
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Product Specifications
Product Name Alternative
KIT||SCFR
Gene Name
KIT
Gene ID
3815
UniProt
P10721
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human CD117 fragment around aa100-300
Target Antigen
CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)
Clonality
Monoclonal
Clone
KIT/982
Applications
WB
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western Blot (1-2ug/ml for 2 hours at RT)
Isotype
Mouse IgG1, kappa
Price
Frequently Asked Questions
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