Monoclonal Antibody to CD11c (Dendritic Cell Marker) (Clone : HC1/1)
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
Product Specifications
Product Name Alternative
ITGAX||CD11C
Gene Name
ITGAX
Gene ID
3687
UniProt
P20702
Host
Mouse
Reactivity
Human
Immunogen
Human monocytic U937 phorbol ester-treated cells
Target Antigen
CD11c (Dendritic Cell Marker)
Clonality
Monoclonal
Clone
HC1/1
Applications
FACS, IF, Functional Assay
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml) ; Functional Studies (Order Ab without BSA & Azide)
Isotype
Mouse IgG1, kappa
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