Monoclonal Antibody to CD50 / ICAM-3 (Clone : SPM505)
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Product Specifications
Product Name Alternative
ICAM3
Gene Name
ICAM3
Gene ID
3385
UniProt
P32942
Host
Mouse
Reactivity
Human
Immunogen
Stimulated human leukocytes
Target Antigen
CD50 / ICAM-3
Clonality
Monoclonal
Clone
SPM505
Applications
FACS, IF, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG2b, kappa
Frequently Asked Questions
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