Monoclonal Antibody to HSP27 (Heat Shock Protein 27) (Clone : SPM252)
Selected Variant
36-1240-100
Size: 100 µg
It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27) . Hsp27 was recently found to be identical to the estrogen-induced p29 and 24K protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.
Product Specifications
Product Name Alternative
HSPB1||HSP27||HSP28
Gene Name
HSPB1
Gene ID
3315
UniProt
P04792
Host
Mouse
Reactivity
Human, Rat, Mouse
Immunogen
Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
Target Antigen
HSP27 (Heat Shock Protein 27)
Clonality
Monoclonal
Clone
SPM252
Applications
FACS, IF, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Price
Frequently Asked Questions
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