Monoclonal Antibody to CD57 / B3GAT1 (Natural Killer Cell Marker) (Clone : SPM129)

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Product Specifications

Product Name Alternative

B3GAT1||GLCATP

Gene Name

B3GAT1

Gene ID

27087

UniProt

Q9P2W7

Host

Mouse

Reactivity

Human

Immunogen

Human peripheral blood mononuclear cells

Target Antigen

CD57 / B3GAT1 (Natural Killer Cell Marker)

Clonality

Monoclonal

Clone

SPM129

Applications

IF, IHC

Purification

Affinity Chromatography

Format

Purified

Components

100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.

Storage Conditions

Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Immunofluorescence (1-2ug/ml) ; Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)