Monoclonal Antibody to Ku (p70/p80) (Nuclear Marker) (Clone : KU729) -PE
Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Product Specifications
Product Name Alternative
XRCC6||G22P1
Gene Name
XRCC6
Gene ID
2547
UniProt
P12956
Host
Mouse
Reactivity
Human
Immunogen
Nuclear extract of human HL-60 cells
Target Antigen
Ku (p70/p80) (Nuclear Marker)
Clonality
Monoclonal
Clone
KU729
Applications
FACS, IF
Purification
Affinity Chromatography
Format
Purified
Components
PE conjugated Ku (p70/p80) Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.
Storage Conditions
Store the antibody at 4°C; stable for 6 months.
Applications Notes
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100 for 30 minutes at RT)
Isotype
Mouse IgG1, kappa
Conjugate
PE
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