Monoclonal Antibody to CD15 / FUT4 (Reed-Sternberg Cell Marker) (Clone : Leu-M1; same as MMA)
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Product Specifications
Product Name Alternative
FUT4||ELFT||FCT3A
Gene Name
FUT4
Gene ID
2526
UniProt
P22083
Host
Mouse
Reactivity
Human
Immunogen
U937 histiocytic cell line
Target Antigen
CD15 / FUT4 (Reed-Sternberg Cell Marker)
Clonality
Monoclonal
Clone
Leu-M1; same as MMA
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgM, kappa
Frequently Asked Questions
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