Monoclonal Antibody to MART-1 / Melan-A / MLANA (Melanoma Marker) (Clone : SPM342)
Selected Variant
36-1128-100
Size: 100 µg
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Product Specifications
Product Name Alternative
MLANA||MART1
Gene Name
MLANA
Gene ID
2315
UniProt
Q16655
Host
Mouse
Reactivity
Human
Immunogen
Recombinant hMART-1 protein
Target Antigen
MART-1 / Melan-A / MLANA (Melanoma Marker)
Clonality
Monoclonal
Clone
SPM342
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG2b, lambda
Price
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