Monoclonal Antibody to Estrogen Receptor, alpha (Marker of Estrogen Dependence) (Clone : ER506), Conjugated with PE-PE
Selected Variant
36-1113-100
Size: 500 μL (100 μg/mL)
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Product Specifications
Product Name Alternative
ESR1||ESR||NR3A1
Gene Name
ESR1
Gene ID
2099
UniProt
P03372
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Estrogen Receptor alpha protein (aa2-185)
Target Antigen
Estrogen Receptor, alpha (Marker of Estrogen Dependence)
Clonality
Monoclonal
Clone
ER506
Applications
FACS, IF
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; , Immunofluorescence (1:50-1:100 for 30 minutes at RT) ;
Isotype
Mouse IgG1, kappa
Conjugate
PE
Price
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