Monoclonal Antibody to HER-2 / c-erbB-2 / neu / CD340 (Clone : ERB2/776)
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Product Specifications
Product Name Alternative
ERBB2||HER2||MLN19||NEU||NGL
Gene Name
ERBB2
Gene ID
2064
UniProt
P04626
Host
Mouse
Reactivity
Human
Immunogen
Recombinant intracellular domain of human HER-2 protein
Target Antigen
HER-2 / c-erbB-2 / neu / CD340
Clonality
Monoclonal
Clone
ERB2/776
Applications
ELISA, FACS, IF
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
ELISA (For coating, order antibody without BSA) ; Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG1, kappa
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