Monoclonal Antibody to EGFR (Epidermal Growth Factor Receptor) (Clone : Clone : GFR450)
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-alphaa), Heparin-binding EGF (HB-EGF), amphiregulin, beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Product Specifications
Product Name Alternative
EGFR||ERBB||ERBB1||HER1
Gene Name
EGFR
Gene ID
1956
UniProt
P00533
Host
Mouse
Reactivity
Human
Immunogen
Recombinant extracellular domain of human EGFR protein
Target Antigen
EGFR (Epidermal Growth Factor Receptor)
Clonality
Monoclonal
Clone
GFR450
Applications
FACS, IF
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)
Isotype
Mouse IgG2a, kappa
Explore Other Products
Browse additional items from our catalog
