Monoclonal Antibody to AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) (Clone : C3)
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop) . This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
Product Specifications
Product Name Alternative
AFP||HPAFP
Gene Name
AFP
Gene ID
174
UniProt
P02771
Host
Mouse
Reactivity
Human
Immunogen
Alpha fetoprotein (AFP) purified from serum of a hepatoma patient
Target Antigen
AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker)
Clonality
Monoclonal
Clone
C3
Applications
IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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