Monoclonal Antibody to p27Kip1 (Mitotic Inhibitor/Suppressor Protein) (Clone : KIP1/769)
This MAb recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF-alpha induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb is excellent for staining of formalin-fixed tissues.
Product Specifications
Product Name Alternative
CDKN1B||KIP1
Gene Name
CDKN1B
Gene ID
1027
UniProt
P46527
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human CDKN1B protein
Target Antigen
P27Kip1 (Mitotic Inhibitor/Suppressor Protein)
Clonality
Monoclonal
Clone
KIP1/769
Applications
FACS, IF, WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa
Frequently Asked Questions
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