Polyclonal Antibody to GIT1 (Ab-383)
Product Specifications
Product Name Alternative
ARF||GAP||CAT-1||CAT1
Gene Name
GIT1
Gene ID
28964
UniProt
Q9Y2X7
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.381~385 (H-D-Y-D-S) derived from Human GIT1 .
Target Antigen
GIT1 (Ab-383)
Clonality
Polyclonal
Applications
WB
Purification
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.Manabe R., Kovalenko M., Webb D.J., Horwitz A.R.J. Cell Sci. 115:1497-1510 (2002)
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blotting :1:500~1:1000
Isotype
Rabbit IgG
Curated Selection
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