Polyclonal Antibody to DLC1 (Ab-868)
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
Product Specifications
Product Name Alternative
ARHGAP7|| KIAA1723|| STARD12
Gene Name
DLC1
Gene ID
10395
UniProt
Q96QB1
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.866~870 (R-N-S-S-S) derived from Human DLC1.
Target Antigen
DLC1 (Ab-868)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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