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Polyclonal Antibody to DLC1 (Ab-868)

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Product Specifications

Product Name Alternative

ARHGAP7|| KIAA1723|| STARD12

Gene Name

DLC1

Gene ID

10395

UniProt

Q96QB1

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.866~870 (R-N-S-S-S) derived from Human DLC1.

Target Antigen

DLC1 (Ab-868)

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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