Polyclonal Antibody to PSMA
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4and isoform PSM-5would appear to be physiologically irrelevant. Involved in prostate tumor progression. Qin B et al. Identification of a LNCaP-specific binding peptide using phage display. Pharm Res 28:2422-34 (2011)
Product Specifications
Product Name Alternative
FGCP|| Folate hydrolase 1|| FOLH|| FOLH1|| GCP2
Gene Name
FOLH1
Gene ID
2346
UniProt
Q04609
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.738~750 (A-A-E-T-L) derived Human from PSMA.
Target Antigen
PSMA
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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