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Polyclonal Antibody to Caveolin-2

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.

Product Specifications

Product Name Alternative

CAV2

Gene Name

CAV2

Gene ID

858

UniProt

P51636

Host

Rabbit

Reactivity

Human

Immunogen

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Target Antigen

Caveolin-2

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

1.0 mg/mL,100 μl

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 18 22kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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