Polyclonal Antibody to Smad1/Smad5/Smad8
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) .SMAD5 is a receptor-regulated SMAD (R-SMAD) . SMAD9 is a receptor-regulated SMAD (R-SMAD) . Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
Product Specifications
Product Name Alternative
Mad-related protein 1||SMAD 1||hSMAD1||Transforming growth factor-beta-signaling protein 1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.461-465 (I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.
Target Antigen
Smad1/Smad5/Smad8
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
1.0 mg/mL,100 μl
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 60kd, Western blotting: 1: 500~1: 1000
Isotype
Rabbit IgG
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