Polyclonal Antibody to IGFBP-3
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Roghani M., Segovia B., Whitechurch O., Binoux M.Growth Regul. 1:125-130 (1991) Ikonen M., Liu B., Hashimoto Y., Ma L. Cohen P.Proc. Natl. Acad. Sci. U.S.A. 100:13042-13047 (2003) Zhou W., Ross M.M., Tessitore A. J. Proteome Res. 8:5523-5531 (2009)
Product Specifications
Product Name Alternative
IBP3|| BP-53
Gene Name
IGFBP3
Gene ID
3486
UniProt
P17936
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.185~189 (R-Y-K-V-D) derived from Human IGFBP-3.
Target Antigen
IGFBP-3 ̄¿1⁄2
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 24-41kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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