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Polyclonal Antibody to CCR5 (CD195)

Receptor for a number of inflammatory CC-chemokines including MIP-1-a, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Product Specifications

Product Name Alternative

CKR5|| CD195|| CKR-5

Gene Name

CCR5

Gene ID

1234

UniProt

P51681

Host

Rabbit

Reactivity

Mouse, Human

Immunogen

Peptide sequence around aa.11~15 (D-I-N-Y-Y) derived from Human CCR5 (CD195) .

Target Antigen

CCR5 (CD195)

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 41kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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