Polyclonal Antibody to CCR5 (CD195)
Receptor for a number of inflammatory CC-chemokines including MIP-1-a, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Product Specifications
Product Name Alternative
CKR5|| CD195|| CKR-5
Gene Name
CCR5
Gene ID
1234
UniProt
P51681
Host
Rabbit
Reactivity
Mouse, Human
Immunogen
Peptide sequence around aa.11~15 (D-I-N-Y-Y) derived from Human CCR5 (CD195) .
Target Antigen
CCR5 (CD195)
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 41kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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