Polyclonal Antibody to E2F-2
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
Product Specifications
Product Name Alternative
E2F-2
Gene Name
E2F2
Gene ID
1870
UniProt
Q14209
Host
Rabbit
Reactivity
Mouse, Human
Immunogen
Peptide sequence around aa.425~429 (L-F-D-S-Y) derived from Human E2F-2.
Target Antigen
E2F-2
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 45kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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