Polyclonal Antibody to DP-1
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis. Wu C.-L., Zukerberg L.R., Ngwu C., Harlow E., Lees J.A.Mol. Cell. Biol. 15:2536-2546 (1995)
Product Specifications
Product Name Alternative
Dp-1|| TFDP1|| DRTF1
Gene Name
TFDP1
Gene ID
7027
UniProt
Q14186
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Peptide sequence around aa.13~17 (E-L-K-V-F) derived from Human DP-1
Target Antigen
DP-1
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 45kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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