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Polyclonal Antibody to Glutamine Synthetase

This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner . Essential for proliferation of fetal skin fibroblasts. Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase." Boksha I.S., Schonfeld H.J., Langen H. Biokhimiia 67:1012-1020 (2002) "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts." Vermeulen T., Goerg B., Vogl T. Arch. Biochem. Biophys. 478:96-102 (2008) "

Product Specifications

Product Name Alternative

GS|| GLNS|| PIG43|| PIG59

Gene Name

GLUL

Gene ID

2752

UniProt

P15104

Host

Rabbit

Reactivity

Rat, Mouse, Human

Immunogen

Peptide sequence around aa.365~369 (G-D-E-P-F) derived from Human Glutamine Synthetase

Target Antigen

Glutamine Synthetase

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 42kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

Curated Selection

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