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Polyclonal Antibody to MELK

Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. Seong H.-A., Gil M., Kim K.-T., Kim S.-J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S. Biol. Chem. 279:8642-8647 (2004)

Product Specifications

Product Name Alternative

HPK38|| KIAA0175|| hMELK

Gene Name

MELK

Gene ID

9833

UniProt

Q14680

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.

Target Antigen

MELK

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 74kd, Western blotting: 1:500

Isotype

Rabbit IgG

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