Polyclonal Antibody to GAPDH
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC By similarity. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.
Product Specifications
Product Name Alternative
G3PD|| GAPD|| MGC88685
Gene Name
GAPDH
Gene ID
2597
UniProt
P04406
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.252~256 (P-A-K-Y-D) derived from Human GAPDH.
Target Antigen
GAPDH
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 37kd, Western blotting: 1:5000~1:10000
Isotype
Rabbit IgG
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
