Polyclonal Antibody to ERAB
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) .
Product Specifications
Product Name Alternative
ABAD|| CAMR|| HCD2|| MHBD|| HADH2
Gene Name
HSD17B10
Gene ID
3028
UniProt
Q99714
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.
Target Antigen
ERAB
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 27kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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