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Polyclonal Antibody to ERAB

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) .

Product Specifications

Product Name Alternative

ABAD|| CAMR|| HCD2|| MHBD|| HADH2

Gene Name

HSD17B10

Gene ID

3028

UniProt

Q99714

Host

Rabbit

Reactivity

Human

Immunogen

Peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.

Target Antigen

ERAB

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 27kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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