Polyclonal Antibody to CK2 Alpha
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation. Keller D.M., Zeng X., et al., Mol. Cell 7:283-292 (2001) Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213 (2002) Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457 (2005) Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684 (2000)
Product Specifications
Product Name Alternative
CKII|| CK2A1|| CSNK2A1
Gene Name
CSNK2A1
Gene ID
1457
UniProt
P68400
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa. 353~357 (S-G-I-S-S) derived from Human CK2?.
Target Antigen
CK2 Alpha
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 42kd, Western blotting: 1:1000
Isotype
Rabbit IgG
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