Polyclonal Antibody to coflin1/cofilin2 (Ab-88)
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830. Arber, S. et al. (1998) Nature 393, 805-809. Yang, N. et al. (1998) Nature 393, 809-812.
Product Specifications
Product Name Alternative
Cofilin|| non-muscle isoform 18 kDa phosphoprotein
Gene Name
CFL1
Gene ID
1072
UniProt
P23528/ Q9Y281
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from Human cofilin1/cofilin2.
Target Antigen
Coflin1/cofilin2 (Ab-88)
Clonality
Polyclonal
Applications
WB, IHC, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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