Polyclonal Antibody to Fibrillarin
Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
Product Specifications
Product Name Alternative
FBL|| FIB|| FLRN|| RNU3IP1
Gene Name
FBL
Gene ID
2091
UniProt
P22087
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.297~301 (L-T-L-E-P) derived from Human Fibrillarin
Target Antigen
Fibrillarin
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 37kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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