Polyclonal Antibody to ASPSCR1
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
Product Specifications
Product Name Alternative
ASPL|| RCC17|| TUG|| UBXD9|| UBXN9
Gene Name
ASPSCR1
Gene ID
79058
UniProt
Q9BZE9
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.
Target Antigen
ASPSCR1
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 70-75kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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