Polyclonal Antibody to Caspase 9
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Product Specifications
Product Name Alternative
ICE-like apoptotic protease 6
Gene Name
CASP9
Gene ID
842
UniProt
P55211
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9
Target Antigen
Caspase 9
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 47 37 35kd, Western blotting: 1:1000
Isotype
Rabbit IgG
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