Polyclonal Antibody to H2B
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product Specifications
Product Name Alternative
H2BQ|| GL105|| H2B.1|| H2BFQ|| H2BGL105
Gene Name
HIST1H2BB
Gene ID
3018
UniProt
P33778
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.
Target Antigen
H2B
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 14kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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