Polyclonal Antibody to BMAL1
ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins Lee S, et al. (2010) PLoS One.5 (6) :e10995. Wang J, et al. (2010) Biosystems.101 (2) :136-43. Jung-Hynes , et al. (2010) J Pineal Res.49 (1) :60-8.
Product Specifications
Product Name Alternative
MOP3|| BMAL1c|| ARNTL|| TIC
Gene Name
ARNTL
Gene ID
406
UniProt
O00327
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.
Target Antigen
BMAL1
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 69kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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