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Polyclonal Antibody to BMAL1

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins Lee S, et al. (2010) PLoS One.5 (6) :e10995. Wang J, et al. (2010) Biosystems.101 (2) :136-43. Jung-Hynes , et al. (2010) J Pineal Res.49 (1) :60-8.

Product Specifications

Product Name Alternative

MOP3|| BMAL1c|| ARNTL|| TIC

Gene Name

ARNTL

Gene ID

406

UniProt

O00327

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa.569~573 (S-S-S-I-L) derived from Human BMAL1.

Target Antigen

BMAL1

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 69kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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