Polyclonal Antibody to TRPC6
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .
Product Specifications
Product Name Alternative
TRP6|| FSGS2|| FLJ11098
Gene Name
Trpc6
Gene ID
22068
UniProt
Q61143
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Target Antigen
TRPC6
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 100kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG
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