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Polyclonal Antibody to TRPC6

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .

Product Specifications

Product Name Alternative

TRP6|| FSGS2|| FLJ11098

Gene Name

Trpc6

Gene ID

22068

UniProt

Q61143

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.

Target Antigen

TRPC6

Clonality

Polyclonal

Applications

WB

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 100kd, Western blotting: 1:500~1:1000

Isotype

Rabbit IgG

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