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Polyclonal Antibody to PKC Zeta (Ab-410)

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Product Specifications

Product Name Alternative

PKC2|| PKC-ZETA|| PRKCZ

Gene Name

PRKCZ

Gene ID

5590

UniProt

Q05513

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa. 408~412 (T-S-T-F-C) derived from PKCz

Target Antigen

PKC Zeta (Ab-410)

Clonality

Polyclonal

Applications

WB, IHC

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 78kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Isotype

Rabbit IgG

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