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Polyclonal Antibody to MAPKAPK-2 (Ab-334)

MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

MAP kinase-activated protein kinase 2

Gene Name

MAPKAPK2

Gene ID

9261

UniProt

P49137

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide sequence around aa.332~336 (P-Q-T-P-L) derived from Human MAPKAPK-2.

Target Antigen

MAPKAPK-2 (Ab-334)

Clonality

Polyclonal

Applications

WB, IF

Format

Purified

Components

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Applications Notes

Predicted MW: 49kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Isotype

Rabbit IgG

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