Polyclonal Antibody to IKK-beta (Ab-199)
Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Product Specifications
Product Name Alternative
I-kappa-B kinase 2|| I-kappa-B-kinase beta|| IKK2|| IkBKB|| NF-KBIKB
Gene Name
IKBKB
Gene ID
3551
UniProt
O14920
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-b.
Target Antigen
IKK- Beta (Ab-199)
Clonality
Polyclonal
Applications
WB, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 87kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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