Polyclonal Antibody to Synaptotagmin 1 (Ab-309)
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10) :3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18 (5) :1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18 (12) :4957-68.
Product Specifications
Product Name Alternative
SYT1|| SytI|| Synaptotagmin I|| P65|| SYT
Gene Name
SYT1
Gene ID
6857
UniProt
P21579
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.307~311 (G-L-S-D-P) derived from Human Synaptotagmin 1.
Target Antigen
Synaptotagmin 1 (Ab-309)
Clonality
Polyclonal
Applications
WB, IF
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 60-65kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Isotype
Rabbit IgG
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